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Object

Title: File of histopathological evaluation of nervous system diseases (1963) - nr 177/63

Date issued/created:

1963

Resource type:

Text

Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

Osetowska, Ewa Prof. dr med

Place of publishing:

Warsaw

Description:

Clinical, anatomical and histological diagnosis

Abstract:

Histological diagnosis: Glioblastome multiforme.Autopsy examination of 68-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin and van Gieson method.An extremely pleomorphic tumor originating from glial tissue was found. In the central parts it contained numerous necrotic and hemorrhagic foci. In the parts distal to the necrotic lesions, three types of tissue were present: perivascular aggregates, sometimes with astroblastoma-like arrangements; loose structureless aggregates of small, poorly differentiated cells, and occasionally single mast cell astrocytes were seen perivascularly - this part of the tumor resembled the structure of glioma immaturum. The peripheral parts showed accumulations of variously shaped cells, often large hyperchromatic cells, although without clear nuclear conglomerates, and numerous cells with abnormal mitoses, spindle cells and astrocyte-like cells. The tumor transitioned indistinctly into an environment in which tumor cells were shuffled with stimulated glial and with retained neurons.

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:210130

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open

Object collections:

Last modified:

Feb 1, 2022

In our library since:

Sep 14, 2021

Number of object content downloads / hits:

15

All available object's versions:

https://rcin.org.pl/imdik/publication/246312

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opis nr 177/63 Feb 1, 2022
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