Title:

CHANGES IN THE CENTRAL NERVOUS SYSTEM IN UREMIC CONDITIONS

Creator:

Osetowska, Ewa ; Mossakowski, Mirosław Jan (1929–2001)

Publisher:

Państwowy Zakład Wydawnictw Lekarskich

Place of publishing:

Warszawa

Date issued/created:

1964

Type of object:

Journal/Article

Subject and Keywords:

uremic conditions ; central nervous system

Abstract:

The morphologic pattern of pathological lesions in the central nervous system associated with uremia is discussed. Three illustrative cases are reported.The first case concerns a 70-year-old female patient in whom uremia was the outcome of a preterminal exacerbation of chronic glomerulonephritis. The morphologic changes in the brain, besides those characteristic of uremic encephalopathy, showed signs of allergic encephalitis typical of para-infectious and postvaccinational encephalitis.The second case concerns a 73-year-old male patient. Uremia was presumably connected with hydronephrosis caused by urinary retention due to prostatic adenomas. The changes in the brain in this case were few, with predominance of edema and moderate atherosclerotic lesions.In the third case, that of a 24-year-old male patient, uremia developed as a result of bilateral destruction of the kidneys by a tuberculous process. The morphological findings in the brain closely resembled those of typical uremic encephalopathy.In all three cases uremia was the result of renal disease, but the pathogenetic mechanism was different in each case. In the opinion of the authors, different pathogenetic mechanisms may be the reason for the different morphological changes in the central nervous system.

Relation:

Polish Medical Journal

Volume:

3

Issue:

2

Start page:

442

End page:

460

Resource type:

Text

Detailed Resource Type:

Article

Format:

pdf

Language:

eng

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open