Contributor:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular

Place of publishing:

Warsaw

Description:

Muscle segment examination in light & electron microscopy

Abstract:

A 26-year-old patient with suspected limb-girdle muscular dystrophy was examined. A biopsy ofquadriceps was performed.Muscle fibers showed normal structure and architecture but electronmicroscopy analysisrevealed significant changes in mitochondria - they were characterized by bright mitochondrialmatrix and were partially or even totally devoid of mitochondrial cristae. Fat droplets were observedwithin the muscle fibers.A defect of mitochondrial enzymes was suspected. Biochemical evaluation of carnitinepalmitoyltransferase in the muscle tissue is advisable.

Detailed Resource Type:

Photography ; Files

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:126502

Language:

pol

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open