Subtitle:

Viral infections in xenotransplantation and their detection strategies

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstract:

Utilizing animals as organ donors for humans may cause transmission of foreign species pathogens to the recipient. To minimize the risk of transmission of infectious diseases from animals to humans, the strategy of appropriate animal selection is being assessed. The aim of the selection of specific pathogen-free pigs was the differentiation of active viruses from latent ones in both the recipients and donors in search of the host gene expression profiles which would differentiate the beginning of transplant rejection from an active infection. Additionally, the researchers searched for gene profile expressions indicating the type of infection which would considerably reduce the time of detection, and the cause of disease in the recipient which would offer a better chance of a positive result of the surgery.

Relation:

Biotechnologia, vol.72, 1 (2006)-.

Volume:

72

Issue:

1

Start page:

125

End page:

132

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:87812 ; IChB B-68

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open