Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
Near the end of the growth phase, mammalian oocyte achieves competence to undergo three aspects of maturation, i.e. nuclear, cytoplasmic and genomic. All these processes are essential for the formation of an egg having the capacity for fertilization and development. This review will consider the aspects of molecular events during the process of nuclear maturation. Meiotic maturation of an oocyte is under the control of the cell cycle molecules, of which cAMP, MPF and MAP kinases seem to be the most important. The present findings regarding Ringo protein and cdc25b kinase as modulators of MPF activity and mechanism of MPF activation are discussed. Moreover, the roles of the FF-MAS, ribo- somal S6 kinase p90''s'<, POLO like kinases and the newly discovered proteins MISS and formin-2 are described.
Biotechnologia, vol.66, 3 (2004)-.
application/pdf ; application/pdf
0860-7796 ; oai:rcin.org.pl:119259
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Oct 2, 2020
Mar 30, 2020
242
https://rcin.org.pl/publication/148514
Opiela, Jolanta Kątska-Książkiewicz, Lucyna
Kątska-Książkiewicz, Lucyna
Kątska-Książkiewicz, Lucyna
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan