Subtitle:

Zastosowanie luliberyny w szczepionkach antykoncepcyjnych

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstract:

Luliberin (luteinizing hormone releasing-hormone, LHRH) is the key regulatory decapeptide that controls reproduction in mammals. It is secreted by thehypothalamus and after binding to a specific receptor it initiates a series ofevents leading to the liberation of lutropin (LH) and finally steroid sex hormones. In some case, the infertility in females and males may be explained bymutations of the LH or LHRH receptor genes. Immunisation of animals withLHRH conjugates induces high titres of antibodies, resulting in the cessation ofthe biological function ofthe hormone and, in the end, in a temporary infertility.

Relation:

Biotechnologia, vol.55, 4 (2001)-.

Volume:

55

Issue:

4

Start page:

47

End page:

54

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:138585 ; IChB B-50

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open