Bączkowski, Krystian ; Mackiewicz, Paweł ; Kowalczuk, Maria ; Banaszak, Joanna ; Cebrat, Stanisław
From sequence to function – looking for genes and their annotations
Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
Today, we have very powerful and effective machines and methods to sequence and analyze DNA sequences. Almost every week, new genomes areadded to sequence databases. However, those data are useless without additional annotations. Genes need to be found and their functions defined. Experimental work is too slow to analyze each sequence of a potential gene but computational methods facilitate such analyses. Here, we review the methodology,potential problems and constraints in genes finding and their annotation. Wedescribe some new approaches including comparative genomics.
Biotechnologia, vol.70, 3 (2005)-.
0860-7796 ; oai:rcin.org.pl:91122 ; IChB B-66
Biblioteka Instytutu Chemii Bioorganicznej PAN
Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Instytut Chemii Bioorganiczneji Polskiej Akademii Nauk
Instytut Chemii Bioorganiczneji Polskiej Akademii Nauk
Oct 2, 2020
Dec 18, 2019
1649
https://rcin.org.pl/ichb/publication/117707
Edition name | Date |
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Od sekwencji do funkcji –poszukiwanie genów i ich adnotacje | Oct 2, 2020 |
Mackiewicz, Paweł Bączkowski, Krystian Sobczyński, Maciej Cebrat, Stanisław
Kowalczuk, Maria Mackiewicz, Dorota Mackiewicz, Paweł Polak, Natalia Cebrat, Stanisław
Tyczewska, Agata Bąkowska- Żywicka, Kamila
Pieczyński, Marcin Bielewicz, Dawid Dolata, Jakub Szweykowska-Kulińska, Zofia