The significance of bile salts hydrolase activity of bacteria of Bifidobacterium genus
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
The objective of this article was to review the existing literature concerning the function and appearance of bile salts hydrolase (BSH) activity in bacteria of Bifidobacterium genus. Although bile salts hydrolase activity is common in intestinal tract, current knowledge on the influence of BSH activity on bile metabolism and cholesterol level in human organism is insufficient. BSH activity of bifidobacteria enhances production of deconjugated bile acids which are not well absorbed by the gut and are excreted. This action is contributing to the decrease of cholesterol level in human organism because cholesterol, as a precursor of bile acids, is utilized for de novo bile acids synthesis.
Biotechnologia, vol.69, 2 (2005)-.
0860-7796 ; oai:rcin.org.pl:111376 ; IChB B-65
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Oct 2, 2020
Jan 31, 2020
349
https://rcin.org.pl/ichb/publication/139452
Edition name | Date |
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Znaczenie aktywności hydrolazy soli żółci u bakterii z rodzaju Bifidobacterium | Oct 2, 2020 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan
Ziarno, Małgrzata Sękul, Ewa Makowska, Monika