Inny tytuł:

Characterization of mammalian oocyte competence to undergo fertilization and embryonic development: I. Nuclear maturation and molecular aspects of its regulation

Wydawca:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstrakt:

Near the end of the growth phase, mammalian oocyte achieves competence to undergo three aspects of maturation, i.e. nuclear, cytoplasmic and genomic. All these processes are essential for the formation of an egg having the capacity for fertilization and development. This review will consider the aspects of molecular events during the process of nuclear maturation. Meiotic maturation of an oocyte is under the control of the cell cycle molecules, of which cAMP, MPF and MAP kinases seem to be the most important. The present findings regarding Ringo protein and cdc25b kinase as modulators of MPF activity and mechanism of MPF activation are discussed. Moreover, the roles of the FF-MAS, ribo- somal S6 kinase p90''s'<, POLO like kinases and the newly discovered proteins MISS and formin-2 are described.

Czasopismo/Seria/cykl:

Biotechnologia, vol.66, 3 (2004)-.

Tom:

66

Zeszyt:

3

Strona pocz.:

140

Strona końc.:

151

Szczegółowy typ zasobu:

Article

Format:

application/pdf ; application/pdf

Identyfikator zasobu:

0860-7796 ; oai:rcin.org.pl:119259

Źródło:

Library of Institute of Bioorganic Chemistry PAS

Język:

pol

Język streszczenia:

eng

Zakres czasowy:

1988-2010

Prawa:

Creative Commons Attribution BY-SA 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitalizacja:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Lokalizacja oryginału:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open