Artificially engineered specific nucleases - a breakthrough in RE research - Rewiev
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
During the last few decades, several hundred type II restriction enzymes have been isolated and characterized from variousbacterial strains, and yet, many specificities are still unavailable.There is an increasing demand for a wider selection of restriction enzymes with varying recognition sequences, which hasstimulated efforts to produce artificial restriction enzymes. Therapidly expanding field of protein engineering couples studies ofprotein structure and function with molecular evolution basedon random mutagenesis and high throughput screening to create enzymes having desired properties.
Biotechnologia, vol.61, 2 (2003)-.
0860-7796 ; oai:rcin.org.pl:135496 ; IChB B-57
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Oct 2, 2020
Aug 18, 2020
36
https://rcin.org.pl/ichb/publication/170467
Edition name | Date |
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Artificially engineered specific nucleases - a breakthrough in RE research - Rewiev | Oct 2, 2020 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan