New, engineered polyketide compounds synthesized by actinomycetes
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
Polyketides constitute a structurally and functionally diverse group of secondary metabolites produced by bacteria, fungi and plants. Macrocyclicpolyketides are produced principally by actinomycetes using modular polyketidesynthases which are giant multienzymes. These enzymes are potentially valuable for the biosynthesis of novel compounds. Engineered, hybrid polyketidesynthases catalyse the formation of simple statin analogues, macrolactone ringanalogues, and biologically active glycosylated compounds.
Biotechnologia, vol.59, 4 (2002)-.
0860-7796 ; oai:rcin.org.pl:137686 ; IChB B-55
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
2 paź 2020
3 wrz 2020
344
https://rcin.org.pl/ichb/publication/172910
Nazwa wydania | Data |
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Nowe związki poliketydowe o zaplanowanej strukturze wytwarzane przez promieniowce | 2 paź 2020 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan