Inny tytuł:

BSE - Identification and prophylactics

Wydawca:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstrakt:

Prion diseases (for example: scrape of sheep, BSE, CJD of humans) areamong the most notable central nervous system degenerative disorders causedby the accumulation of modified cellular protein. The conversion of PrP(C) (thenormal cellular protein) into PrP(Sc) (the abnormal disease-causing isoform) involves a conformation change whereby the a-helical content diminishes and theamount of P sheet increases. PrP (Sc) is partially resistant to proteases, temperature, high and low pH. Because the incidence of prion diseases is due to severalfactors, various efforts need to be taken to reduce the scale and consequencesof the disease. They include post-mortem and in vivo diagnosis and prophylactics, i.e. monitoring of animals and feed control.

Czasopismo/Seria/cykl:

Biotechnologia, vol.56, 1 (2002)-.

Tom:

56

Zeszyt:

1

Strona pocz.:

136

Strona końc.:

141

Szczegółowy typ zasobu:

Article

Format:

application/pdf

Identyfikator zasobu:

0860-7796 ; oai:rcin.org.pl:138406 ; IChB B-52

Źródło:

Library of Institute of Bioorganic Chemistry PAS

Język:

pol

Język streszczenia:

eng

Zakres czasowy:

1988-2010

Prawa:

Creative Commons Attribution BY-SA 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitalizacja:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Lokalizacja oryginału:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open