Zastosowanie luliberyny w szczepionkach antykoncepcyjnych
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
Luliberin (luteinizing hormone releasing-hormone, LHRH) is the key regulatory decapeptide that controls reproduction in mammals. It is secreted by thehypothalamus and after binding to a specific receptor it initiates a series ofevents leading to the liberation of lutropin (LH) and finally steroid sex hormones. In some case, the infertility in females and males may be explained bymutations of the LH or LHRH receptor genes. Immunisation of animals withLHRH conjugates induces high titres of antibodies, resulting in the cessation ofthe biological function ofthe hormone and, in the end, in a temporary infertility.
Biotechnologia, vol.55, 4 (2001)-.
0860-7796 ; oai:rcin.org.pl:138585 ; IChB B-50
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
2 paź 2020
11 wrz 2020
852
https://rcin.org.pl/ichb/publication/173907
Nazwa wydania | Data |
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Zastosowanie luliberyny w szczepionkach antykoncepcyjnych | 2 paź 2020 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan