Campbell, K. H. S. ; Ritchie, W. ; Loi, P. ; McWhir, J. ; Wilmut, I.
The role of cell cycle co-ordination in the development of nuclear transfer reconstructed embryos
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
Exciting new opportunities in embryo cloning have been made possible by recent studies onthe interaction of the donor nucleus with the recipient cytoplasm following embryo reconstruction. The purpose of this paper is to review information regarding the co-ordination of nuclearand cytoplasmic events during embryo reconstruction, in particular the direct and indirect effectsof maturation/meiosis/mitosis promoting factor (MPF), upon the transferred nucleus. These willbe discussed in relation to DNA replication, the maintenance of correct ploidy, the occurrenceof chromosomal abnormalities and development of reconstructed embryos. Although this reviewis primarily concerned with the reconstruction of mammalian embryos, specific examples fromamphibians will also be cited.
Biotechnologia, vol.33, 2 (1996)-.
0860-7796 ; oai:rcin.org.pl:147103 ; IChB B-29
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
13 lis 2020
13 lis 2020
52
https://rcin.org.pl/ichb/publication/182727
Nazwa wydania | Data |
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The role of cell cycle co-ordination in the development of nuclear transfer reconstructed embryos | 13 lis 2020 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan