Inny tytuł:

Structure, expression and engineering of miik protein genes

Wydawca:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstrakt:

Expression of milk protein genes is regulated by hormones, growth factors and extracellularmatrix. Prolactin, the major lactogenic hormone, promotes all stages of casein gene expression.Besides prolactin, also growth hormone may directly induce expression of milk protein genes.Computer analysis, mutation experiments and DNA-protein binding experiments enabled identification of mammary-specific transcription factors and cis-regulatoiy sequences in milk proteingene promoters. Also, transgene technology enables recognition of regulatory sequences in milkprotein genes. Moreover, transgenic animals carrying structural genes of human proteins fusedto mammary specific promoters are considered as living “bioreactors” designated to producehuman proteins for pharmaceutical use.

Czasopismo/Seria/cykl:

Biotechnologia, vol.33, 2 (1996)-.

Tom:

33

Zeszyt:

2

Strona pocz.:

81

Strona końc.:

94

Szczegółowy typ zasobu:

Article

Format:

application/pdf

Identyfikator zasobu:

0860-7796 ; oai:rcin.org.pl:147104 ; IChB B-29

Źródło:

Library of Institute of Bioorganic Chemistry PAS

Język:

eng

Język streszczenia:

eng

Zakres czasowy:

1988-2010

Prawa:

Creative Commons Attribution BY-SA 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitalizacja:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Lokalizacja oryginału:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open