Screening methods of industrial strain mutants
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
The screening methods used for improvement of industrial strains are presented. Two generalcategories of methods have been distinguished: random screening and rational screening. Majortechniques employed in rational screening are based on the selection of auxotrophic mutants,revertants of non-producers, strains resistant to some factors like toxic analogues of metabolismintermediates, induction and catabolite repression or end-product inhibition, mutants with modified cell wall permeability and microorganisms tolerating some nutrients and precursors ofsecondary metabolites.
Biotechnologia, vol.30, 3 (1995)-.
0860-7796 ; oai:rcin.org.pl:147667 ; IChB B-26
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Nov 19, 2020
Nov 19, 2020
173
https://rcin.org.pl/ichb/publication/183232
Edition name | Date |
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Metody skriningu mutantów drobnoustrojów przemysłowych | Nov 19, 2020 |
Galas, Edward Kwapisz, Ewa Siwińska, Krystyna
Galas, Edward Kwapisz, Ewa Tarabasz-Szymańska, Łucja Krystynowicz, Alina Antczak, Tadeusz Oryńska, Agnieszka
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan