Recycling of eucaryotic ribosomes
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
Until recently protein biosynthesis has been viewed as a process involving only three steps: initiation of translation, elongation of the nascent polypeptide chain and release of the completed unfolded polypeptide. In recent years fourth step in translation has been distinguished - it is the recycling of the ribosome. In this process posttermination complexes termed post-TC consisting of ribosomes with deacylated tRNA(s) and mRNA are dissociated with the help of ribosome recycling factor (RRF), elongation factor G (EF-G) and initiation factor 3 (1F3) in Procaryotes. The mechanism of this final step in Eucaryotes was unknown for a long time, but the work of Pisarev et al. sheds a light on splitting 80S ribosomes and preparing them for the next cycle of translation.
Biotechnologia, vol.84, 1 (2009)-.
0860-7796 ; oai:rcin.org.pl:73113 ; IChB B-79
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Oct 2, 2020
Jun 15, 2019
85
https://rcin.org.pl/ichb/publication/95764
Edition name | Date |
---|---|
Recycling of eucaryotic ribosomes | Oct 2, 2020 |
Tyczewska, Agata Bąkowska- Żywicka, Kamila
Tyczewska, Agata Bąkowska-Żywicka, Kamilla
Bąkowska-Żywicka, Kamilla Tyczewska, Agata
Sławińska, Anna Siwek, Maria
Pieczyński, Marcin Bielewicz, Dawid Dolata, Jakub Szweykowska-Kulińska, Zofia