Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

Mossakowski, M.J dr med.

Place of publishing:

Warsaw

Description:

Clinical, anatomical and histological diagnosis

Abstract:

Histological diagnosis: Encephalomalacia alba partim haemorrhagica recens.Autopsy examination of 82-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin and van Gieson method.A right parietal region specimen showed a necrotic focus involving both the cortex and the white matter. The cortex was almost completely devoid of nerve cells. The preserved nerve cells showed increased retrograde changes of ischemic type. The greatest number of preserved nerve cells was found in layer II and in layer V. Glial cells were maintained. The population of glial cells in the white matter was preserved. The structure of the cortex and white matter was loosened, with a picture of spongy lesions in places. The vessels mostly showed obliteration of their normal structure and significant endothelial stimulation. Perivascular dense clusters of leukocytes were observed. Leukocytes were also seen lying freely in the tissue. Some sections of the cortex showed very numerous perivascular hemorrhages by diapedesis, comprising the typical picture of hemorrhagic necrosis. The soft meninges showed leukocytic infiltrates and red cell masses.

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:210113

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open