Department of Experimental and Clinical Neuropathology MMRI
Clinical, anatomical and histological diagnosis
Histological diagnosis: Focus encephalomalaciae inveteratus putaminis sin. Haemorrhagia pontis.Autopsy examination of 56-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin and van Gieson method.The putamen showed an old foci of malacia with well advanced fibroblastic organization filling the post-malacic cyst with the loose network. Few hemosiderin-laden macrophages were visible in the network. Numerous vessels were present, markedly atherosclerotic, with thrombi organizing in the lumen. On 2 specimens in small vessels an accumulation of dark-blue rod-shaped structures was observed, filling the entire lumen (putrefactive bacteria?). The vessels in the vicinity of the focus also showed severely advanced atherosclerotic lesions. Several fresh extravasations with a tendency to cluster into one large focus were found within the pons.
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Mossakowski Medical Research Institute PAS
Library of the Mossakowski Medical Research Institute PAS
Feb 1, 2022
Sep 14, 2021
26
https://rcin.org.pl/imdik/publication/246293
Edition name | Date |
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opis nr 133/63 | Feb 1, 2022 |