Biodegradation of N-heterocyclic compound
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
N-heterocyclic aromatic compounds are common contaminants associated withthe use of hydrocarbons in both coal gasification and wood treatment processes. Those compounds have been found in groundwater, and many are known mutagens. It isobvious that in many cases the removal of those toxic compounds from our environment is a very complicated and expensive process. A method looking very promisingis the one which employs the strains of chosen microorganisms and their biochemicalpathways for biodegradation of a number ofvery dangerous compounds like pyridine,quinoline, carbazole and derivatives ofthese compounds. Pyridine could be degradedthrough the same pathway under both aerobic and anaerobic conditions. The firststep in this process is hydration. The mechanism of pyridine degradation involvesN-C-2 (Nocardia Zl) or C-2-C-3 [Bacillus 4) ring cleavage. The metabolism of pyridinederivatives and other N-heterocyclic compounds like quinoline, carbazole or indoleseems to be initiated by hydroxylation. The initial step in the transformation anda ring cleavage of quinoline derivatives can occur on either the heterocyclic or the homocyclic ring
Biotechnologia, vol.48, 1 (2000)-.
0860-7796 ; oai:rcin.org.pl:142196 ; IChB B-44
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Oct 12, 2020
Oct 9, 2020
159
https://rcin.org.pl/publication/177566
Edition name | Date |
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Biodegradacje związków N-heterocyklicznych | Oct 12, 2020 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan