Inny tytuł:

Chemical Combinatorial Libraries — Their Synthesis and Applications

Wydawca:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstrakt:

The paper reviews the new methodologies of synthesis and screening of combinatorial libraries of chemical compounds (CCL). The original classification of chemical combinatorial librariesis presented. The combinatorial libraries of chemical compounds are the collections of low (peptides, their analogues, oligonucleotides etc.) or high molecular compounds (fragment antibodies,chemically modified phages etc.). They can be obtained via chemical or chemical/biological routesand screened with labelled acceptor (substrate) molecules in order to reveal those of interactinglibrary entities which best meet the selection criteria (conditions of selection). The potentialapplications of CCLs in basic research and technology are indicated.

Czasopismo/Seria/cykl:

Biotechnologia, vol.32, 1 (1996)-.

Tom:

32

Zeszyt:

1

Strona pocz.:

162

Strona końc.:

175

Szczegółowy typ zasobu:

Article

Format:

application/pdf

Identyfikator zasobu:

0860-7796 ; oai:rcin.org.pl:147322 ; IChB B-28

Źródło:

Library of Institute of Bioorganic Chemistry PAS

Język:

pol

Język streszczenia:

eng

Zakres czasowy:

1988-2010

Prawa:

Creative Commons Attribution BY-SA 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitalizacja:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Lokalizacja oryginału:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open