Nucleic acid in sifu hybridization; from ISH to DIRVISH
Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
In situ hybridization (ISH) provides a highly sensitive method for the detection of specificnucleic acid sequences in cells, nuclei and metaphase chromosomes. This technique has beenimproved continuously since it was first established in 1969. Especially fluorescent in situ hybridization (FISH) rapidly replaced radioactive procedures and became a conventional tool incytogenetic research. ISH plays an increasingly important role in a variety of research areas ofmedicine, genetics and plant breeding. It has been successfully applied for chromosome orchromosome fragments identification, chromosomal abnormalities detection, gene mapping orspecific DNA sequences localization.
Biotechnologia, vol.29, 2 (1995)-.
0860-7796 ; oai:rcin.org.pl:147872 ; IChB B-25
Biblioteka Instytutu Chemii Bioorganicznej PAN
Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Nov 20, 2020
Nov 20, 2020
1291
https://rcin.org.pl/publication/183456
Edition name | Date |
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Hybrydyzacja kwasów nukleinowych in situ: od ISH do DIRVISH | Nov 20, 2020 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan
Nowak, Jacek K.