Inny tytuł:

Oligonucleotides as potential therapeutic tools against hepatitis C virus

Wydawca:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstrakt:

Hepatitis C virus belongs to the group of particularly dangerous and most extensively studied RNA viruses. Since no vaccine for HCV is known and post-exposure treatment of infected patients has not been yet optimal, novel therapeutic strategies are being developed very intensively. Oligonucleotide-based molecular tools such as antisense oligonucleotides, ribozymes, DNAzymes, aptamers and interfering RNAs are proving as effective modulators of gene expression and potential therapeutics. Several examples of oligonucleotide-based molecular tools directed towards HCV viral RNA are discussed in this review.

Czasopismo/Seria/cykl:

Biotechnologia, vol.88, 1 (2010)-.

Tom:

88

Zeszyt:

1

Strona pocz.:

13

Strona końc.:

33

Szczegółowy typ zasobu:

Article

Format:

application/pdf

Identyfikator zasobu:

0860-7796 ; oai:rcin.org.pl:71733 ; IChB B-83

Źródło:

Library of Institute of Bioorganic Chemistry PAS

Język:

pol

Język streszczenia:

eng

Zakres czasowy:

2010

Prawa:

Creative Commons Attribution BY-SA 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitalizacja:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Lokalizacja oryginału:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open