Production of paclitaxel and other taxanes in in vitro cultures
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
KULTURY IN VITRO I BIOTECHNOLOGIA ROŚLIN
Paclitaxel is an effective important anticancer drug for advanced breast,ovarian and other cancers. It was first isolated from the bark of the Pacific yew(Taxus brevifolia). Paclitaxel belongs to a group of secondary metabolites collectively indicated with the name taxanes. Paclitaxel is found in most yews, but thecontent is very (0-0,05%) variable. Because of the scarcity of the slow growingtrees and the relative low content of paclitaxel, alternative sources are neededto meet the increasing demand. The literature concerning the tissue culture ofTaxus sp. as an alternative source for taxanes production in reviewed.
Biotechnologia, vol.62, 3 (2003)-.
0860-7796 ; oai:rcin.org.pl:133141 ; IChB B-58
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
2 paź 2020
21 lip 2020
504
https://rcin.org.pl/publication/167806
Nazwa wydania | Data |
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Wytwarzanie paklitakselu i innych taksanów w kulturach in vitro | 2 paź 2020 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan