MicroRNAs (miRNAs) are an abundant group of endogenous small (—22) noncoding RNAs, found both in plants and animals. The total number of sequences encoding miRNA in genomes of these organisms is estimated to be of all genes. miRNAs derive from longer precursor transcripts which adopt a fold- back structure. Mature miRNAs are incorporated into ribonucleoprotein complexes miRNPs and take part in negative control of genes’ expression by cleavage of mRNAs or inhibition of the translation. miRNAs influence a great range of biological processes, such as cell proliferation, stem cell maitenance, timing of cell fate in developmental process, organ morphogenesis, programmed cell death and fat metabolism.
Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.
Oct 2, 2020
Dec 19, 2019
|Mikrozarządzanie||Oct 2, 2020|
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