Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
Many yeasts secrete proteins which are toxic for pathogenic and non-pathogenic microorganisms. These toxins, mostly glycoproteins, consist of membrane-binding subunits which interact with carbohydrates (e.g. 1,6-|3-D-glucanor a-mannan) on the cell wall ofsensitive strains. The killing effect is presentedby membrane permeation, cell lysis or inhibition of the cell cycle.It is also suggested that these killer glycoproteins, similar in structure tolectins, can mediate self-adhesion ofthe pathogenic microorganisms, thus stimulating their excretion from the intestines of infected mammals. It is supposedthat the above interactions could be important for therapeutic applications, especially for enteric diseases.
Biotechnologia, vol.55, 4 (2001)-.
0860-7796 ; oai:rcin.org.pl:138606 ; IChB B-50
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
2 paź 2020
11 wrz 2020
78
https://rcin.org.pl/publication/173957
Nazwa wydania | Data |
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Yeast antimicrobial proteins | 2 paź 2020 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan
Salek, Anna Teresa
Salek, Anna Teresa
Salek, Anna Teresa
Salek, Anna Teresa
Salek, Anna Teresa