RCIN and OZwRCIN projects

Object

Title: Structure, expression and engineering of miik protein genes

Creator:

Zwierzchowski, Lech

Date issued/created:

1996

Resource type:

Tekst

Subtitle:

Structure, expression and engineering of miik protein genes

Publisher:

Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN

Abstract:

Expression of milk protein genes is regulated by hormones, growth factors and extracellularmatrix. Prolactin, the major lactogenic hormone, promotes all stages of casein gene expression.Besides prolactin, also growth hormone may directly induce expression of milk protein genes.Computer analysis, mutation experiments and DNA-protein binding experiments enabled identification of mammary-specific transcription factors and cis-regulatoiy sequences in milk proteingene promoters. Also, transgene technology enables recognition of regulatory sequences in milkprotein genes. Moreover, transgenic animals carrying structural genes of human proteins fusedto mammary specific promoters are considered as living “bioreactors” designated to producehuman proteins for pharmaceutical use.

Relation:

Biotechnologia, vol.33, 2 (1996)-.

Volume:

33

Issue:

2

Start page:

81

End page:

94

Detailed Resource Type:

Artykuł

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:147104 ; IChB B-29

Source:

Biblioteka Instytutu Chemii Bioorganicznej PAN

Language:

eng

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0

Terms of use:

-

Digitizing institution:

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Original in:

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Projects co-financed by:

Program Operacyjny Polska Cyfrowa, lata 2014-2020, Działanie 2.3 : Cyfrowa dostępność i użyteczność sektora publicznego; środki z Europejskiego Funduszu Rozwoju Regionalnego oraz współfinansowania krajowego z budżetu państwa

Access:

Otwarty

Object collections:

Last modified:

Nov 13, 2020

In our library since:

Nov 13, 2020

Number of object content downloads / hits:

30

All available object's versions:

https://rcin.org.pl/publication/182730

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