Cywińska, Urszula ; Iciek, Jan ; Chmiel, Aleksander ; Stolarek, Paweł
Continuous sterilization of medium for bacitracin biosynthesis
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
The aim of the paper was to estimate the applicability of continuous sterilization to theimprovement of bacitracin production technology. Preliminary investigations were carried outand the effects of application of thermal continuous sterilization of substrates were estimated.The quality of sterilized substrates was assessed in fermentation tests. Bacitracin biosynthesiswas carried out on a substrate sterilized by both batch and continuous method. In laboratoryinvestigations a substrate sterilized by the continuous method enabled to increase antibioticproduction by 30% on the average as compared to the yield obtained using a batch sterilizedsubstrate. On an industrial scale, for the same inoculation material the production was evenhigher by 80%.
Biotechnologia, vol.21, 2 (1993)-.
0860-7796 ; oai:rcin.org.pl:155728 ; IChB B-17
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Jan 21, 2021
Jan 21, 2021
347
https://rcin.org.pl/publication/189973
Edition name | Date |
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Sterylizacja ciągła podłoża do biosyntezy bacytracyny | Jan 21, 2021 |
Iciek, Jan Cywińska, Urszula Stolarek, Paweł
Iciek, Jan Cywińska, Urszula Stobińska, Helena Stolarek, Paweł
Kiljański, Tomasz Cywińska, Urszula Iciek, Jan Nowakowska, Krystyna Piotrowski, Michał
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan
Iciek, Jan