The application of monoclonal antibodies to medical treatment
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
In this review contemporary trends in the application of monoclonal antibodies are presented.There is discussed antibody reengineering for humanization of mouse monoclonal antibodies toavoid anti-globulin reaction of patient. Recent modifications of antibody fragments are also outlined. The most common antigenic structures exposed to antibody attack are characterized. Someaspects of human monoclonal antibody production are briefly described. Three most promisingtherapeutic antibodies — bispecific antibodies, immunotoxins, and radiolabeled immunoconjugates — are presented.
Biotechnologia, vol.21, 2 (1993)-.
0860-7796 ; oai:rcin.org.pl:155731 ; IChB B-17
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Jan 21, 2021
Jan 21, 2021
545
https://rcin.org.pl/publication/189985
Edition name | Date |
---|---|
Wykorzystanie przeciwciał monoklonalnych do celów terapeutycznych | Jan 21, 2021 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan