Twórca instytucjonalny:

Department of Experimental and Clinical Neuropathology MMRI

Współtwórca:

E.Osetowska, dr hab.

Miejsce wydania:

Warsaw

Opis:

Clinical, anatomical and histological diagnosis

Abstrakt:

Histological diagnosis:Ecncephalitis lymphocytaria acuta.Autopsy examination of 14-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain frozen sections stained with Hematoxylin-eosin.The predominant feature of the case was acute perivascular and pericellular edema in both white and grey matter. Perivascular transudates were seen in the white matter. A distinct edematous "halo" was observed around oligodendrocytes and astrocytes, causing fiber tracts in the white matter to be dispersed. In the cortex, especially the parietal region, spongy thinning of the structure was seen in several places. Medium and small vessels were filled with blood. Around the medium-sized vessels, sparse lymphocytic infiltrates consisting of several to dozens of elements were visible in the walls. The structure of the cerebral cortex and grey nuclei was preserved - individual cells were obliterated with tigrolysis. The meninges showed venous stasis, slight lymphocytic and mesothelial infiltrates. The picture corresponds to very acute, "fulminant" lymphocytic encephalitis, occurring spontaneously or accompanying infectious diseases (most often in the course of influenza epidemics).

Format:

pdf

Identyfikator zasobu:

oai:rcin.org.pl:213878

Język:

pol

Język streszczenia:

eng

Prawa:

Creative Commons Attribution BY 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitalizacja:

Mossakowski Medical Research Institute PAS

Lokalizacja oryginału:

Library of the Mossakowski Medical Research Institute PAS

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open