The synthesis of the aromatic amino acid L-phenylalanine has received considerable attention in recent years due to its increasing importance as precursorto the dipeptide sweetener aspartame. Phenylalanine ammonia lyase (PAL), whichoccurs in yeast, catalyzes the nonoxidative deamination of L-Phe to trans-cinnamicacid (tCA), has industrial application in the synthesis of L-Phe. Superior producers of PAL are Rhodotorula sp. PAL is induced in yeast cell by the presence ofL-Phe, while glucose represses PAL synthesis. Different additives and conditionsduring inducing PAL: permeabilizing, reducing and stabilization agents, as wellas pH and temperature during bioconversion targeting to higher productivity ofL-Phe were discussed.
Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.
Feb 18, 2020
Dec 11, 2019
|Biokonwersja kwasu frans-cynamonowego do L-fenyloalaniny przez drożdże z rodzaju Rhodotorula||Feb 18, 2020|
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